Growth of hepatitus A virus in vero cells
US4783407A · kind A · utility
18Cited by
2References
8Claims
0Family size
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Key dates
| Filing date | Sep 30, 1985 |
| Grant date | Nov 8, 1988 |
| Priority date | — |
| Expiry date | Sep 30, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Hepatitus A virus is grown in Vero cells after passage in in vitro cell culture. Virus replication and continued passage in Vero cells requires extended incubation times, up to about four weeks, for early passages and incubation temperatures no higher than about 32.degree. C. Continued passage results in a significant decrease in incubation time and an increase in virus yield. Cultivation of hepatitus A virus in Vero cells meets the development requirements for an inactivated human vaccine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.