Production of streptococcal m protein immunogens and molecular probes
US4784948A · kind A · utility
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41Claims
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Key dates
| Filing date | Jun 18, 1984 |
| Grant date | Nov 15, 1988 |
| Priority date | — |
| Expiry date | Jun 18, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/806
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the cloning and expression of Streptococcus pyogenes M protein genes, and, in particular, types 5, 6 and 24 genes in single-cell host organisms. The streptococcal M protein produced by the recombinant DNA techniques described herein may be formulated for use as immunogens in vaccines to protect against S. pyogenes infections. The gene for the M protein may further be employed as a molecular probe for the accurate identification of streptococci in infected body tissues and fluids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.