Substantially pure cytotoxicity triggering factor
US4785077A · kind A · utility
14Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 5, 1986 |
| Grant date | Nov 15, 1988 |
| Priority date | — |
| Expiry date | May 5, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/827
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new, human proteinaceous lymphokine denominated cytotoxicity triggering factor (CTF) is disclosed as are methods of its preparation and use. Substantially pure CTF has an apparent M.sub.r of about 55 kd, is capable of inducing secretion of a tumor-killing factor containing tumor necrosis factor-alpha from primed monocytes, and is substantially free from pyrogen as well as interferon-gamma, interleukin-2 and direct cytotoxin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.