Dry sustained release theophylline oral formulation
US4786509A · kind A · utility
9Cited by
4References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 18, 1987 |
| Grant date | Nov 22, 1988 |
| Priority date | — |
| Expiry date | May 18, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A sustained release theophylline containing oral dosage formulation comprising theophylline containing micropellets coated with from about 0.5% to about 2% by weight of a pharmaceutically acceptable water-insoluble film former, preferably ethyl cellulose and having first order release. The formulation is an improvement over theophylline containing micropellets coated with two film formers which have zero order release. The oral dosage formulation has superior non-fasting release and absorption characteristics when compared to the zero order release formulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.