Process for determining the binding capacity of thyroxin-binding globulin

US4786591A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Brigitte Draeger · Tutzing, DE
• Winfried Albert · Eberfing, DE
• Martina Junius · Bernried, DE
• Jurgen Rasch · Tutzing, DE

Key dates

• Filing date: Dec 23, 1986
• Grant date: Nov 22, 1988
• Expiry date: Dec 23, 2006

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/817
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides a process for determining the binding capacity of thyroxin-binding globulin (TBG) according to the principle of heterogeneous enzyme immunoassay, wherein the serum sample to be investigated is incubated with enzyme-labelled T.sub.4 or T.sub.3 and immobilized antibody against TBG or T.sub.4, the phase are separated and the labelling enzyme is measured in one of the phases.