Treatment of allograft rejection with mycophenolic acid morpholinoethylester and derivatives thereof
US4786637A · kind A · utility
36Cited by
1References
4Claims
0Family size
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Key dates
| Filing date | Jan 22, 1988 |
| Grant date | Nov 22, 1988 |
| Priority date | — |
| Expiry date | Jan 22, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds and pharmaceutical compositions of Formula A, wherein Z is hydrogen or --C(O)R, Y is hydrogen or morpholinoethyl, and where R is lower alkyl or aryl, and the pharmaceutically acceptable salts thereof, are useful as immunosuppressive agents, particularly for treatment of allograft rejection, especially including cardiac allograft rejection, pancreatic allograft rejection and renal allograft rejection, and for treating autoimmune diabetes. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.