Resolution of enantiomers of 2-(4-aryloxyphenoxy) propionic acids by liquid chromatography with a chiral eluent
US4786732A · kind A · utility
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Key dates
| Filing date | Aug 5, 1987 |
| Grant date | Nov 22, 1988 |
| Priority date | — |
| Expiry date | Aug 5, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for the effective chromatographic resolution and analysis of the enantiomers of 2-(4-aryloxyphenoxy)propionic acids which comprises dissolving a 2-(4-aryloxyphenoxy)propionic acid in a suitable solvent, injecting the solution into a liquid chromatographic system and eluting the components from the column using an eluent contain R-(-)- or S-(+)-2-pyrrolidinemethanol and an alkanoic acid in a suitable solvent.
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