Method for separating liquid compositions on the basis of molecular weight
US4789482A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1986 |
| Grant date | Dec 6, 1988 |
| Priority date | — |
| Expiry date | Feb 10, 2006 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D2313/14
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
An ultrafiltration device comprising hollow fibers or thin channels through which ultrafiltration of blood plasma is effected is operated under conditions of tangential flow and low conversion. A recirculation stream of high molecular weight fraction of the liquid stream is fed to the device and a permeate stream from the device is recovered. The optimum module aspect ratio is designed and the corresponding maximum shear rate of incoming liquid is specified and controlled so as to provide maximum separation efficiency (selectivity and flux) allowing for separation between species of similar size or molecular weight. Shear rate is controlled by controlling the recirculation stream flow rate. The ratio of the transmembrane pressure at the channel outlet to the transmembrane pressure at the channel inlet resulting from the optimal design and operation is also specified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.