Benzamido-derivatives

US4789683A · kind A · utility

Assignee

• Astra Lakemedel Aktiebolag · SE

Inventors

• Gosta Lennart Florvall · Gately Drive, SE
• Jan O. G. Lundstrom · Sollentuna, SE
• Sten I. Ramsby · Gately Drive, SE
• Sven O. gren · Gately Drive, SE

Key dates

• Filing date: Jan 8, 1985
• Grant date: Dec 6, 1988
• Expiry date: Jan 8, 2005

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel therapeutically active compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and each represents a hydrogen atom, a halogen atom, a cyano group, a lower alkyl group or an acyl group, R.sup.3 is a lower alkyl group; an alkenyl group; or a benzyl group optionally substituted with fluorine, chlorine, bromine, trifluoromethyl, lower alkyl or lower alkoxy, A.sup.1 and A.sup.2 are the same or different and each represents a hydrogen atom, a lower alkyl group, an acyl group, an alkoxycarbonyl group or a dialkylcarbamyl group, provided that when A.sup.1 and A.sup.2 are the same lower alkyl group and R.sup.3 is ethyl, R.sup.1 or R.sup.2 or both are selected among cyano, lower alkyl and acyl; or a physiologically acceptable salt or optical isomers thereof, methods for their preparation, pharmaceutical preparations containing the compounds and methods for their therapeutical use.