Process for the preparation of 2,4-diamino-5-benzylpyrimidines
US4789743A · kind A · utility
3Cited by
2References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 31, 1987 |
| Grant date | Dec 6, 1988 |
| Priority date | — |
| Expiry date | Jul 31, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparaton of compounds of the formula I by reacting an alkali metal alcoholate with a compound of the formula II in the presence of an aliphatic ester such as methyl formate, and then condensing guanidine with the resulting compound of the formula III. The compound of the formula II can be prepared by reacting the corresponding benzaldehyde with acrylonitrile in the presence of diazabicyclo-2,2,2,-octane. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.