Process for the resolution of enantiomeric aryloxyphenoxy propionates
US4789744A · kind A · utility
2Cited by
1References
3Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 5, 1987 |
| Grant date | Dec 6, 1988 |
| Priority date | — |
| Expiry date | Aug 5, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the effective analytical or preparative resolution of the enantiomers of 2-(4-aryloxyphenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof which comprises converting a racemic or partially resolved mixture of said 2-(4-aryloxyphenoxy)propionic acids or the C.sub.1 -C.sub.4 alkyl esters thereof to a pair of diastereomeric terpene esters by reaction with an optically active terpene alcohol and separating the diastereomers of the terpene ester by liquid chromatography with a silica column.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.