Potentiating formulations
US4795639A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1977 |
| Grant date | Jan 3, 1989 |
| Priority date | — |
| Expiry date | Mar 16, 1997 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/635
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for testing or treating microbial systems or infections, comprising an effective potentiating amount of a microbial dihydropteridine antagonist, which itself inhibits hydroxymethyldihydropteridine pyrophospokinase and has a sufficiently low toxicity, in combination with an effective amount of a competitor of para-aminobenzoic acid or an inhibitor of dihydrofolate reductase or both, its method of preparation, and its use in the inhibition of the production of dihydrofolic acid by microorganisms under in vivo or in vitro conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.