Patent · US Expired

Potentiating formulations

US4795639A · kind A · utility

3Cited by
2References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 16, 1977
Grant dateJan 3, 1989
Priority date
Expiry dateMar 16, 1997

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/635
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A composition for testing or treating microbial systems or infections, comprising an effective potentiating amount of a microbial dihydropteridine antagonist, which itself inhibits hydroxymethyldihydropteridine pyrophospokinase and has a sufficiently low toxicity, in combination with an effective amount of a competitor of para-aminobenzoic acid or an inhibitor of dihydrofolate reductase or both, its method of preparation, and its use in the inhibition of the production of dihydrofolic acid by microorganisms under in vivo or in vitro conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.