Medicament with a delayed release of active ingredient
US4795643A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 29, 1987 |
| Grant date | Jan 3, 1989 |
| Priority date | — |
| Expiry date | Jun 29, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/4858
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In addition to the active ingredient, the capsules contain a nonionic surfactant consisting of a polyglycol ester or ether having hydrophilic and lipophilic portions, and an organic polymer which is capable of forming a free-flowing composition with the active ingredient and the surfactant. The essential point for the delay in release is the matching of the water-solubility of the active ingredient and the hydrophilic/lipophilic character (HLB value) of the surfactant as follows: ______________________________________ water-insoluble HLB value above 16; sparingly soluble HLB value between 10 and 16; and water-soluble HLB value below 10. ______________________________________
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.