Method of inhibiting HIV
US4795739A · kind A · utility
30Cited by
0References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 29, 1987 |
| Grant date | Jan 3, 1989 |
| Priority date | — |
| Expiry date | May 29, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting expression of HIV antigens in human blood cells infected with HIV. The infected cells are exposed to a plant protein or glycoprotein, such as trichosanthin or momorcharin, at a concentration sufficient to (a) produce a substantial reduction in the level of HIV antigen, and (b) effect a selective reduction in the number of HIV-infected cells, with respect to uninfected cells of the same type. The method is used to treat HIV infection in humans. In another aspect, the invention includes a method of screening drug agents effective in treating HIV infection in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.