Phospholipid affinity purification of Factor VIII:C
US4795806A · kind A · utility
23Cited by
7References
11Claims
0Family size
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Key dates
| Filing date | Jul 16, 1987 |
| Grant date | Jan 3, 1989 |
| Priority date | — |
| Expiry date | Jul 16, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Affinity purification of Factor VIII:C, both plasma derived and genetically engineered, using coupled phosphatidylserine (PS) as the predominant phospholipid (PH) results in a high degree of purity of Factor VIII:C, similar to that previously demonstrated with monoclonal antibodies specific to either Factor VIII:C or von Willebrand factor. Phospholipids that can be used in combination with PS are phosphatidycholine (PC) and phosphatidylethanolamine (PE).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.