Novel clavam derivatives and methods of making same
US4795809A · kind A · utility
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1References
2Claims
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Key dates
| Filing date | Aug 27, 1986 |
| Grant date | Jan 3, 1989 |
| Priority date | — |
| Expiry date | Aug 27, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/465
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A compound having the formula (I): ##STR1## is described, together with salts thereof and an enzymatic process for converting such compounds into clavulanic acid. A process for the preparation of the compound of formula (I) and its salts is disclosed, together with intermediates for use therein. This process involves the use of a novel enzyme system to effect the desired cyclization, which enzyme system is preferably derived from a micro-organism, in particular a species of Streptomyces.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.