Well-type diagnostic plate device
US4797259A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1986 |
| Grant date | Jan 10, 1989 |
| Priority date | — |
| Expiry date | Dec 15, 2006 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/54366
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A diagnostic test device is provided including a plate having at least one well, preferably a plurality of wells, each with an open bottom across which a composite membrane comprising three layers is placed, with a hydrophobic, liquid-tight seal provided at the periphery of each well. The composite membrane from the top of upstream side to the bottom or downstream side, in sequence, includes a first reaction or filtration layer formed from a thin, liquophilic, microporous membrane, a second or sealing layer, preferably a hydrophobic material in sheet or fiber form, such as nonwoven polypropylene fibers, and a liquophobic, preferably hydrophobic, barrier layer having one or more apertures which allows liquid to exit the well while eliminating lateral migration of a pendant liquid drop. The liquophobic seal provided by the liquophobic sealing layer eliminates "cross-talk" by lateral diffusion or wicking.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.