Patent · US Expired

Bis-platinum complexes as chemotherapeutic agents

US4797393A · kind A · utility

14Cited by
5References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 1986
Grant dateJan 10, 1989
Priority date
Expiry dateJul 25, 2006

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A bis-platinum complex having the structure: ##STR1## wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt.sup.2+. The complexes are useful in the inhibition of tumors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.