Bis-platinum complexes as chemotherapeutic agents
US4797393A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1986 |
| Grant date | Jan 10, 1989 |
| Priority date | — |
| Expiry date | Jul 25, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A bis-platinum complex having the structure: ##STR1## wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt.sup.2+. The complexes are useful in the inhibition of tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.