Peptide derivatives having an inhibitory action on hydroxylating enzymes, a process for their preparation, agents containing them, and their use

US4797471A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Volker Teetz · Hofheim, DE
• Stephan Henke · Bad Soden am Taunus, DE
• Dietrich Brocks · Wiesbaden, DE
• Hartmut Hanauske-Abel · Edgewater, US
• Volkmar Gunzler · Marburg, DE

Key dates

• Filing date: Dec 12, 1986
• Grant date: Jan 10, 1989
• Expiry date: Dec 12, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/0815
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to peptide derivatives of the formula ##STR1## in which ##STR2## represents an acyl radical, B represents the radical of a dipeptide composed of a N.sup..omega. -acylated basic .alpha.-amino acid and another .alpha.-amino acid, and W represents hydroxyl or optionally substituted amino, to a process for their preparation, to agents containing them, and to their use.