Adamantyl- and fluorenyl-arylpiperazines and -arylpiperidines
US4797489A · kind A · utility
17Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 2, 1987 |
| Grant date | Jan 10, 1989 |
| Priority date | — |
| Expiry date | Dec 2, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds ##STR1## wherein R.sup.1 is 1-adamantyl, 3-methyl-1-adamantyl, 9-fluorenyl or 1-fluorenyl; PA1 n is 0 or 1; PA1 m is 1, 2, 3, 4 or 5; and PA1 X is ##STR2## where R.sup.2 is phenyl, benzyl, pyridinyl, pyrimidinyl, pyrazinyl or substituted phenyl or benzyl in which the substituent is alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, halo, cyano, nitro or trifluoromethyl, ##STR3## where R.sup.3 is hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, halo, cyano or nitro; or pharmaceutically acceptable salts thereof are useful antidepressant and/or anxiolytic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.