Synergistin derivatives and pharmaceutical compositions which contain them
US4798827A · kind A · utility
6Cited by
4References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 21, 1987 |
| Grant date | Jan 17, 1989 |
| Priority date | — |
| Expiry date | May 21, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides new synergistin derivatives of formula ##STR1## in which Y is hydrogen or dimethylamino and R is a 3- or 4-quinuclidinyl radical, the isomers thereof and their mixtures, and their salts, also the preparation thereof. These compounds may be made by reaction of the corresponding 5-methylene compounds with the appropriate mercaptoquinuclidine. The products of formula (I), optionally combined with pristinamycin II.sub.A or a derivative of pristinamycin II.sub.B of the formula ##STR2## are useful as antimicrobials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.