Process for preparing levomepromazine hydrogen maleate
US4798895A · kind A · utility
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Key dates
| Filing date | Jun 24, 1987 |
| Grant date | Jan 17, 1989 |
| Priority date | — |
| Expiry date | Jun 24, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D279/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Levomepromazine hydrogen maleate is prepared by resolving (.+-.)-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine with (-)-di(p-toluoyl)-L-tartaric acid to produce the neutral salt of the dextrorotatory base and then adding maleic acid to the mother liquors to precipitate the levomepromazine hydrogen maleate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.