Preparation of solid pharmaceutical forms

US4801460A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Helmut Goertz · Ludwigshafen, DE
• Roger Klimesch · Ransbach-Baumbach, DE
• Klaus Laemmerhirt · Haßloch, DE
• Siegfried Lang · Ludwigshafen, DE
• Axel Sanner · Bischofswerda, DE
• Reinhard Spengler · Frankenthal (Pfalz), DE

Key dates

• Filing date: Apr 6, 1987
• Grant date: Jan 31, 1989
• Expiry date: Apr 6, 2007

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B29K2105/0035
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Process for the preparation of solid pharmaceutical forms by mixing one or more pharmaceutical active compounds with one or more fusible, pharmacologically tolerated binders and, if required, other conventional pharmaceutical auxiliaries, at from 50.degree. to 180.degree. C., and subjecting the mixture to injection molding or extrusion and shaping, wherein the fusible binder used is a NVP polymer which contains not less than 20% by weight of NVP as copolymerized units, and, where they are present, all of whose comonomers contain nitrogen and/or oxygen.