Patent · US Expired

Guanidinobenzoic ester derivative

US4801603A · kind A · utility

2Cited by
4References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 24, 1986
Grant dateJan 31, 1989
Priority date
Expiry dateDec 24, 2006

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D263/44
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula: EQU --OR in which R is a hydrogen atom or a lower alkyl group, and n represents an integer of 1 to 5.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.