Guanidinobenzoic ester derivative
US4801603A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 24, 1986 |
| Grant date | Jan 31, 1989 |
| Priority date | — |
| Expiry date | Dec 24, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A guanidinobenzoic ester derivative having the formula is novel and effective to inhibit enzymes such as trypsin, plasmin and thrombin, being useful for treatment of the pancreatitis and hemorrhagic disease and thrombosis. ##STR1## wherein X represents a group of the formula: ##STR2## in which Y is a group of the formula: --(CH.sub.2).sub.m --, m being an integer of 2 or 3, ##STR3## or a group of the formula: EQU --OR in which R is a hydrogen atom or a lower alkyl group, and n represents an integer of 1 to 5.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.