Reagent paper for immunologically analysis, a process for the preparation thereof and the use thereof

US4803171A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Manfred Baier · Starnberg, DE
• Klaus P. Kaspar · Tutzing, DE
• Rainer Schafer · Schneeberg, DE
• Ulrich Trager · Schifferstadt, DE
• Siegfried Notzel · Wilhelmsfeld, DE

Key dates

• Filing date: Dec 11, 1986
• Grant date: Feb 7, 1989
• Expiry date: Dec 11, 2006

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/81
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention provides a process for the preparation of a reagent paper for immunological analysis, wherein a fiber fleece of a cellulose/synthetic fiber mixture, in which the weight ratio of cellulose/synthetic fiber is 1 to 90/99 to 10, is activated by treatment with periodate, the so activated fiber fleece is loaded with an acid-treated protein and non-bound protein is removed. The present invention also provides a reagent paper for immunological analysis, wherein it comprises a fiber fleece of a cellulose/synthetic fiber mixture, in which the weight ratio of cellulose/synthetic fiber is from 1 to 90/99 to 10. Furthermore, the present invention is concerned with the use of a fiber fleece of a cellulose/synthetic fiber mixture, wherein the weight ratio of cellulose/synthetic fiber is 90 to 1/10 to 99, as reagent carrier for heterogeneous immunological analysis.