Hypoglycemic 2',3',10'-tetrahydro-10'-hydroxy-10'-substituted-spiro[cycloakane-1,3'-p yrimido(1,2-a)indole]deratives
US4803207A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 9, 1987 |
| Grant date | Feb 7, 1989 |
| Priority date | — |
| Expiry date | Mar 9, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pyrimidoindoles of formula (I) ##STR1## and their pharmaceutically acceptable acid addition salts, wherein R represents lower alkyl a mono- or bicyclic aryl radical or a group of mormula R.sup.3 O--B--[where R.sup.3 O is (lower)alkoxy,aryl(lower)alkoxy or hydroxy and B is a lower alkylene chain optionally containing one double or triple bond], R.sup.1 and R.sup.2 which may be the same or different each represent hydrogen, hydroxyl, lower alkyl, lower alkoxy, halo(lower)alkyl, halogen, amino or mono- or di(lower) alkylamino and A, together with the carbon atom to which it is attached, represents 5, 6 or 7 membered saturated carbocyclic or heterocyclic ring, are useful as hypoglyceamics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.