Norfloxacin intermediate
US4803274A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 7, 1987 |
| Grant date | Feb 7, 1989 |
| Priority date | — |
| Expiry date | Aug 7, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of compounds of the Formula I ##STR1## (wherein R and R.sup.1 stand for an aliphatic acyloxy group comprising 2-5 carbon atoms and optionally substituted by halogen or for an aromatic acyloxy group comprising 7-11 carbon atoms), which comprises reacting a compound of the general Formula II ##STR2## (wherein R.sup.2 stands for hydrogen or alkyl comprising 1-4 carbon atoms) with a boron derivative of the Formula III ##STR3## (wherein R.sup.3, R.sup.4 and R.sup.5 stand for an alkyl group comprising 1-4 carbon atoms and optionally substituted by halogen or for an aryl group comprising 6-10 carbon atoms). The new compounds of the general Formula I are useful pharmaceutical intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.