Preparation of 4(5)-nitroimidazole-5(4)-carboxylic acids

US4803283A · kind A · utility

Assignee

• BASF SE

Inventors

• Toni Dockner
• Uwe Kempe · Schifferstadt, DE
• Hermann Koehler · Beindersheim, DE

Key dates

• Filing date: Nov 30, 1987
• Grant date: Feb 7, 1989
• Expiry date: Nov 30, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/92
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

4(5)-nitroimidazole-5(4)-carboxylic acids are prepared by reacting an imidazole-4(5)-carboxylic acid with a mixture of sulfuric acid and nitric acid at not less than 80.degree. C., the water content of the reaction mixture at the beginning of the reaction being no higher than 5% by weight, based on the reaction mixture.