Use of specific relaxation agents for organs or pathologies for modifying the contrasts in medical imaging by nuclear magnetic resonance
US4804529A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 10, 1984 |
| Grant date | Feb 14, 1989 |
| Priority date | — |
| Expiry date | Aug 10, 2004 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to specific relaxation agents for organs or pathologies, which can be used for modifying the contrasts in medical imaging by nuclear magnetic resonance. These agents are constituted by a complex of a paramagnetic element having a biologically active ligand or a ligand coupled to a biologically active molecule and which is specific to an organ or pathology. Thus, they are selectively fixed to the organs and make it possible to modify the contrasts in imaging by nuclear magnetic resonance, due to the presence of the paramagnetic element, which modifies the relaxation times. For example, when examining the kidney, the complex can be constituted by dimercaptosuccinate or gadolinium diethylene triaminopentaacetate, whilst gadolinium phytate is used in examinations of the liver.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.