Substituted 4-(1H-imidazol-1-yl)benzamides as antiarrhythmic agents

US4804662A · kind A · utility

Assignee

• Schering A.G. · DE

Inventors

• Klaus Nickisch · Berlin, DE
• Randall E. Lis · Stanhope, US
• William C. Lumma, Jr. · Pennsburg, US
• Thomas K. Morgan, Jr. · Morristown, US
• Ronald A. Wohl · Morristown, US

Key dates

• Filing date: May 5, 1987
• Grant date: Feb 14, 1989
• Expiry date: May 5, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel substituted 4-[1H-imidazol-1-yl]benzamides and their use in the treatment of cardiac arrthythmias especially as Class III or combination Class I/III antiarrhythmic agents is described. Pharmaceutical formulations containing such compounds are also disclosed.