Patent · US Expired

Method and compositions for reducing neurotoxic injury

US4806543A · kind A · utility

112Cited by
0References
17Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 25, 1986
Grant dateFeb 21, 1989
Priority date
Expiry dateNov 25, 2006

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/28
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for reducing adverse effects of neurotoxic injury, which comprises administering to a patient susceptible to neurotoxic injury an effective amount, sufficient to reduce the injury, of a compound which is an enantiomer of an analgesic opioid agonist or antagonist, preferably an opiate agonist having a ring system of the following stereochemistry, which shows only carbon and nitrogen atoms in the rings: ##STR1## The dextrorotatory opiates, dextrorphan and dextromethorphan, are particularly suitable for use in the method of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.