Antihypercholesterolemic beta-lactones
US4806564A · kind A · utility
15Cited by
3References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 1987 |
| Grant date | Feb 21, 1989 |
| Priority date | — |
| Expiry date | May 26, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of the following structural formula (I) ##STR1## are 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) synthase inhibitors and useful as antihypercholesterolemic agents for the treatmet of disease in which the inhibition of cholesterol biosynthesis would be useful, such as arteriosclerosis, hyperlipidemia and familial hypercholesterolemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.