Composition for diagnosing the transport function of the fallopian tube and a method for preparing said composition
US4808399A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 11, 1986 |
| Grant date | Feb 28, 1989 |
| Priority date | — |
| Expiry date | Dec 11, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0091
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention pertains to a preparation for diagnosing the transport function of the fallopian tube and to a method for making such a preparation. The diagnostic preparation for investigation of the transport function of female fallopian tube, comprises a suspension of a biocompatible, biodegradable, and, if desired, labelled particles, in a vehicle commonly used for parenteral applications wherein the particles have a spherical shape with diameters in the region 10 to 600 um, which are formed from a soft hydrophilic gel based on a polymer selected from the group comprising additionally crosslinked water-soluble nontoxic and biodegradable inert polysaccharides and physiologically inert water-soluble and biodegradable poly(amino acids), polypeptides, and their derivatives, which may contain physiologically active substances. The particles retain their shape and size in the environment of peritoneal cavity and uterotubal tract for at least 80 hours with the subsequent degradation to nontoxic product within 5 to 60 days. A method for preparation of the diagnostic preparation comprises dispersing an aqueous solution of physilogically inert, biodegradable polymer selected from t…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.