Use of 2,5-anhydro-D-mannitol as a food intake modifier
US4808626A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 23, 1986 |
| Grant date | Feb 28, 1989 |
| Priority date | — |
| Expiry date | Sep 23, 2006 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel method for altering the food intake of a mammal is disclosed wherein 2,5-anhydro-D-mannitol (2,5-AM) is administered to that mammal in an amount sufficient to alter its food intake. Preferably, normal feeding and fasting periods, and most preferably diurnal feeding and fasting periods, are identified. The mammal receives an intragastric, or intraperitoneal, or intravenous administration within two hours in advance of the onset of the feeding period to decrease food intake, or within two hours of the onset of the fasting period to increase intake. The subject mannitol is preferably administered in amounts of 50-800 mg/kg, although neither the lower limit of sufficiently nor the upper limit of activity have yet to be identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.