Volume independent diagnostic device
US4810470A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1987 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Jun 19, 2007 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/525
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A process and device for quantitative determination of analyte concentrations in liquid samples. The device includes one or more bibulous matrices constructed and arranged to essentially eliminate sample volume sensitivity from analyte determinations. In accordance with the present invention, the device includes one or more test reagent-treated bibulous matrices covered at least partially by an impermeable coating or film. A liquid sample is applied to the uncovered portion of the bibulous matrix such that the liquid sample is metered into the bibulous matrix by the impermeable coating or film. The sample chromatographs through the bibulous matrix until the matrix is saturated with liquid. The process is essentially sample volume independent, providing more uniform and accurate quantitative analyte determinations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.