Physically modified beclomethasone dipropionate suitable for use in aerosols
US4810488A · kind A · utility
30Cited by
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10Claims
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Assignee
Inventor
Key dates
| Filing date | Aug 18, 1986 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Aug 18, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J5/0076
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing a stable aerosol formulation of beclomethasone dipropionate in which the steroid is contacted with an alcohol containing 1 to 5 carbon atoms to form a crystalline solvate therewith, the crystalline material so formed being reduced to a particle size below 10 microns and thereafter dispersed in a composition comprising chlorofluorocarbon propellents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.