Specific binding assays employing label analog to reduce sample interferences
US4810635A · kind A · utility
12Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 16, 1986 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Apr 16, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/825
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A specific binding assay, e.g., immunoassay, method and reagent system wherein a structural analog of the label portion of the labeled reagent is included in the reaction mixture to interact with potentially interfering substances in the test sample. The label analog is selected or designed to be substantially inactive in the assay detection system. The invention improves the precision of the assays, particularly homogeneous immunoassays, by significantly reducing or eliminating the variable interaction, e.g., binding, of the labeled reagent by interfering substances in the test sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.