Enzyme-labeled antibody reagent with polyalkyleneglycol linking group
US4810638A · kind A · utility
22Cited by
1References
8Claims
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Key dates
| Filing date | Jul 24, 1986 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Jul 24, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/964
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Enzyme-labeled antibody reagents wherein the enzyme and an antibody reagent, e.g., whole polyclonal or monoclonal antibody or a fragment thereof, are covalently linked through a bis-maleimidopolyalkyleneglycol bridge group. The reagents are useful in immunoassay and other methods for detecting an antigen or hapten that can be bound by the antibody reagent. The conjugates are highly stable and water soluble, and are characterized by a high degree of immunoreactivity and enzyme activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.