Patent · US Expired

Haloarylnitrile degrading gene, its use, and cells containing the gene

US4810648A · kind A · utility

247Cited by
1References
25Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 8, 1987
Grant dateMar 7, 1989
Priority date
Expiry dateJul 8, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/8274
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Nitrilase enzymes specific for the hyrdolsis of the nitrile group of bromoxynil, nucleotide sequences encoding for such enzymes, and transformed cells in which the nitrilase expression if foreign are provided. The transformed cells are capable of expressing the nitrilase enzyme to provide detoxification of an environment and protect bromoxynil-sensitive cells from its cytotoxic effect. Particularly, plants are developed which are resistant to bromoxynil. PA0 E. coli MM294 strain (pBrx5) was deposited at the A.T.C.C. on Jan. 22, 1986 and given Accession no. 53435. PA0 E. coli MM294 strain (pBrx11) was deposited at the A.T.C.C. on June 18, 1987 and given Accession no. 67441. PA0 E. coli MM294 strain (pBrx23) was deposited at the A.T.C.C. on June 18, 1987 and given Accession no. 67442.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.