Triazolo [3,4-b]pyridazines, process for their preparation and pharmaceutical compositions containing them
US4810705A · kind A · utility
9Cited by
8References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 1987 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Jun 10, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to 1,2,4-triazolo [4,3-b]pyridazines substituted in the 7-position of formula: ##STR1## in which R represents hydrogen, a lower alkyl group, a phenyl group, a chlorophenyl group or a benzyl group and R.sub.1 represents a phenyl, halogenophenyl, trifluoromethylphenyl, lower alkyl-phenyl or lower alkoxy-phenyl group or a phenyl-lower alkyl group, or one of its pharmaceutically acceptable salts. Said compounds antagonize the effects of benzodiazepines and therefore are useful as antidotes in the abuse of benzodiazepines and compounds acting on benzodiazepine receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.