Intermediates for preparing 1,6-dicarba-vasopressin compounds
US4810778A · kind A · utility
2Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1988 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | May 9, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/15
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New compounds which have potent V.sub.2 -vasopressin antagonistic activity are prepared by a 1,6-cyclization using peptide bond formation. The structures of the compounds are characterized by the Pas.sup.1,6 or Tas.sup.1,6 cyclized unit. Also a chiral synthesis of the optically pure Pas intermediates is described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.