Pyrrolobenzimidazoles, pharmaceutical compositions containing them, and use of them to treat certain heart and circulatory diseases

US4810801A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Alfred Mertens · Schriesheim, DE
• Jens-Peter Holck · Mannheim, DE
• Wolfgang Kampe
• Bernd Muller-Beckmann · Bamberg, DE
• Klaus Strein · Hemsbach, DE
• Wolfgang Schaumann · Heidelberg, DE

Key dates

• Filing date: Oct 1, 1987
• Grant date: Mar 7, 1989
• Expiry date: Oct 1, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/42
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides new pyrrolobenzimidazoles of the general formula: ##STR1## wherein R.sub.1 -R.sub.5, X and T are as defined in the specification. The present invention also provides processes for the preparation of these compounds and pharmaceuticals containing them for the prophylaxis and treatment of heart and circulatory diseases.