Aspartyl-beta substituted phenylalanine dipeptides
US4810817A · kind A · utility
3Cited by
13References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 1, 1987 |
| Grant date | Mar 7, 1989 |
| Priority date | — |
| Expiry date | Oct 1, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspartame or derivative by enzymatic coupling of phenylserine or derivative with aspartic acid or derivative. Hydrogenation of the coupled product to give as final product aspartame or analog with related processes and products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.