Tripeptide renin inhibitors
US4812442A · kind A · utility
22Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 4, 1987 |
| Grant date | Mar 14, 1989 |
| Priority date | — |
| Expiry date | May 4, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Enzyme tripeptides of the formula: ##STR1## and analogs thereof which inhibit renin and are useful for treating various forms of renin-associated hypertension, hyperaldosteronism and congestive heart failure; compositions containing these renin-inhibitory peptides, optionally with other antihypertensive agents; and methods of treating hypertension, hyperaldosteronism or congestive heart failure or of establishing renin as a causative factor in these problems employing the novel tripeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.