3-phenyl-1-propanones, process of preparing thereof and method of treating arrhythmias
US4814330A · kind A · utility
Inventor
Key dates
| Filing date | Mar 11, 1987 |
| Grant date | Mar 21, 1989 |
| Priority date | — |
| Expiry date | Mar 11, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutically useful 1-[3-(2-dialkylaminoethoxy)-2-thienyl]-3-phenyl-1-propanones of the formula ##STR1## and acid addition salts thereof, wherein R and R.sub.1 each are hydrogen or methyl, PA0 R.sub.2 and R.sub.3, which are the same or different, each are alkyl, cycloalkyl, alkenyl or alkynyl each containing up to 8 carbon atoms, or PA0 R.sub.2 and R.sub.3 together with the nitrogen atom to which they are attached form a 5 to 7-membered saturated ring or a saturated heterocyclic ring which may contain optionally an oxygen or nitrogen atom as further hetero atom in the ring, a further nitrogen atom being unsubstituted or substituted by an alkyl radical containing 1 to 3 carbon atoms. The compounds are useful for the treatment of various disturbances of the heart rhythm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.