Process for preparing 3 halogeno-2-hydroxypropyltrimethylammonium halide
US4814506A · kind A · utility
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4Claims
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Assignee
Inventors
Key dates
| Filing date | Aug 21, 1987 |
| Grant date | Mar 21, 1989 |
| Priority date | — |
| Expiry date | Aug 21, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C215/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing 3-halogeno-2-hydroxy-propyltrimethylammonium halide or especially one having the (S)-configuration, which comprises reacting 2,3-dihydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is obtained by reacting (R)-3-halogeno-1,2-propanediol with trimethylamine, with a halogenating reagent. According to the present invention, 3-halogeno-2-hydroxypropyltrimethylammonium halide or one having the (S)-configuration, which is a useful intermediate for the synthesis of carnitine or especially (l)-carnitine, can be obtained economically, efficiently and easily.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.