Patent · US Expired

Ingestible aggregate and delivery system prepared therefrom

US4818539A · kind A · utility

28Cited by
48References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 29, 1988
Grant dateApr 4, 1989
Priority date
Expiry dateFeb 29, 2008

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K9/5073
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to an ingestible aggregate comprising a pre-swelled substantially anhydrous hydrocolloid and a substrate. More particularly this invention relates to an aggregate having as a substrate a dietary fiber and/or drug wherein the composition can be administered in a therapeutically effective amount. Hydrocolloids useful include natural and modified gums, celluloses, modified celluloses, pectins, mucillages, modified starches, noncellulose polysaccharides, algal polysaccharides and mixtures thereof. The aggregate should be in the size range of about 4 to about 70 U.S. mesh. The unpleasant taste and mouthfeel of the fiber and/or drug is effectively masked and substantial hydration is delayed until the composition reaches the stomach. The compositions are substantially more palatable, devoid of graininess, bitterness or fibrous texture. The pleasant taste of the composition encourages patient compliance with their fiber or drug therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.