2-pyrimidinyl-1-piperazine derivatives, processes for their preparation and medicaments containing them

US4818756A · kind A · utility

Assignee

• Troponwerke GmbH & Co. KG · DE

Inventors

• Peter-Rudolf Seidel · Cologne, DE
• Harald Horstmann
• Jorg Traber · Lohmar, DE
• Wolfgang Dompert · Cologne, DE
• Thomas Glaser · Overath, DE
• Teunis Schuurman · Overath, DE

Key dates

• Filing date: Mar 10, 1986
• Grant date: Apr 4, 1989
• Expiry date: Mar 10, 2006

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to substituted 2-pyrimidinyl-1-piperazine derivatives defined herein by formula (I), processes for their manufacture, compositions containing said substituted 2-pyrimidinyl-1-piperazine derivatives as active materials and the use of said compounds and compositions as agents effecting the central nervous system. Also included in the invention are intermediates of formula (VIII) for making the active formula (I) compounds.