Derivatives of pyridylsulfinyl(benz-or thieno-)imidazoles and their use as gastric secretion inhibiting substances
US4818760A · kind A · utility
16Cited by
5References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1987 |
| Grant date | Apr 4, 1989 |
| Priority date | — |
| Expiry date | Sep 9, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel derivatives of 4,5-dihydrooxazoles of the formula ##STR1## in which A denotes --CH.dbd.CH-- or --S--, PA1 R.sub.1, R.sub.3 and R.sub.4, independently of one another, denote hydrogen or lower alkyl, PA1 R.sub.2 denotes hydrogen or lower alkoxy, and PA1 n denotes 0 or 1, a process for their preparation, and pharmaceutical preparations which contain these compounds. The novel compounds cause blockage of H.sup.+ /K.sup.+ ATPase and can be used as active ingredients in medicaments for treatment and prophylaxis of disorders which are caused by increased gastric secretions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.