Cardiac electrode with drug delivery capabilities
US4819662A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 26, 1987 |
| Grant date | Apr 11, 1989 |
| Priority date | — |
| Expiry date | Oct 26, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0568
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An implantable cardiac pacing lead includes a porous, platinum electrode, a flexible electrically conductive coil, and a crimp tube coupling the electrode to the distal end of the coil. A recess in the crimp tube, open to the electrode at the crimp tube distal end, houses a matrix impregnated with a therapeutic drug. The electrode is highly porous and loaded with a therapeutic drug in liquid or solid form. Immediately upon implant of the electrode at a selected myocardial location, the electrode begins dispensing the therapeutic drug. Meanwhile, the matrix begins to elute its drug at a rate more suited to chronic treatment. If desired, the recess can extend through the crimp tube to permit proximal end loading of the drug carrying matrix. A silicone plug, or an additional and proximal crimp tube section, is inserted into the recess after loading of the matrix to provide the required fluid seal. Finally, a variety of different matrices can be housed in the recess, to provide elution of different drugs and at differing rates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.